Decongestion in Acute Heart Failure

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Decongestion in Acute Heart Failure

SEE PAGE 580 F luid overload and the resultant signs and symptoms, such as dyspnea, are the predominant factors precipitating a hospitalization for acute heart failure. The first-line treatment to relieve this congestion are loop diuretic agents, which are administered to more than 90% of patients hospitalized for acute heart failure (1). Heart failure guidelines recommend treatment with escala...

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Decongestion strategies and renin-angiotensin-aldosterone system activation in acute heart failure.

OBJECTIVES The purpose of this study was to assess the relationship between biomarkers of renin-angiotensin-aldosterone system (RAAS) activation and decongestion strategies, worsening renal function, and clinical outcomes. BACKGROUND High-dose diuretic therapy in patients with acute heart failure (AHF) is thought to activate the RAAS; and alternative decongestion strategies, such as ultrafilt...

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Markers of decongestion, dyspnea relief, and clinical outcomes among patients hospitalized with acute heart failure.

BACKGROUND Congestion is a primary driver of symptoms in patients with acute heart failure, and relief of congestion is a critical goal of therapy. Monitoring of response to therapy through the assessment of daily weights and net fluid loss is the current standard of care, yet the relationship between commonly used markers of decongestion and both patient reported symptom relief and clinical ou...

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Heart Failure Potential Effects of Aggressive Decongestion During the Treatment of Decompensated Heart Failure on Renal Function and Survival

Background—Overly aggressive diuresis leading to intravascular volume depletion has been proposed as a cause for worsening renal function during the treatment of decompensated heart failure. If diuresis occurs at a rate greater than extravascular fluid can refill the intravascular space, the concentration of such intravascular substances as hemoglobin and plasma proteins increases. We hypothesi...

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Acute heart failure (AHF) is a life-threatening emergency, which largely profits from early diagnosis and treatment. The prevalence of AHF is difficult to assess, estimates range between 1 and 12% in the general population. Despite recent therapeutic advances, in-hospital mortality is high with estimates varying from 4 and 18% in different registries. Due to large differences in AHF definitions...

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ژورنال

عنوان ژورنال: JACC: Heart Failure

سال: 2016

ISSN: 2213-1779

DOI: 10.1016/j.jchf.2016.03.024